The most important ingredients

Niacinamide

Vitamin B3 - one of the most versatile actives, working on pores, pigment and the skin barrier.

Function: Can visually minimise pores, ease pigment spots, strengthen the skin barrier and ease redness.

Vitamin C

The most important water-soluble antioxidant of the skin.

Function: Can brighten the complexion, support resilience, ease pigment spots and protect from UV damage.

Salicylic acid

The only fat-soluble fruit acid (BHA) - can penetrate into the pores, where water-based acids cannot reach.

Function: Can unclog pores, clear blemishes and soothe irritated skin.

Azelaic acid

Naturally occurring acid (also produced by yeasts on the skin) with multiple effects.

Function: Can ease blemishes, redness and pigment spots at the same time - one of the most versatile actives.

Application

Apply a thin layer in the evening to the cleansed, pigmented skin areas. Distribute evenly and leave to work overnight.

Use as directed by your doctor - frequency and amount are adjusted individually. Always use sunscreen with at least SPF 50 during the day.

Frequently asked questions

What is cosmelan 2 and can I use it without a prior treatment?

No. cosmelan 2 is the home care phase of the cosmelan system. It only comes into use after the cosmelan 1 treatment in the practice. Without the prior treatment it is not effective as a standalone brightener.

What is the difference between cosmelan 2 and other brightening creams?

cosmelan 2 is not a standalone product but the professionally accompanied home phase. The prior treatment (cosmelan 1) intensively disrupts the melanin cycle - cosmelan 2 then maintains this result and prevents reactivation.

What is the exact dosing schedule in the 3 phases?

Phase 1 (intensive): First 1 to 2 weeks, once daily in the evening, maximum concentration. You will notice dryness and mild flaking - that is the process. Phase 2 (consolidation): weeks 3 to 6, every other day in the evening. Phase 3 (maintenance): from week 7, twice weekly.

Can I interrupt cosmelan 2 if my skin gets irritated?

You should discuss that with your treating practitioner, not on your own. Brief pauses (1 to 2 days) are possible without losing progress - longer interruptions should be agreed with the practice.

Can I use cosmelan 2 in the sun or only in winter?

cosmelan 2 is ideally started in periods of lower sun intensity (autumn/winter) because the skin is more sensitive during the treatment and UV can trigger new pigmentation. Sun protection SPF 50+ daily is mandatory during the entire treatment period.

About the brand

mesoestetic is a Spanish company with over 40 years of experience in active-ingredient cosmetics. Its strength lies in highly dosed ingredients - the cosmelan system in particular is a worldwide reference for pigment spots. If you are looking for targeted correction of stubborn skin concerns such as an uneven complexion or first signs of skin ageing, you will find products here with high, tested active concentrations.

Transparency & Mandatory Information

Ingredients (INCI)

Aqua, Caprylic/Capric Triglyceride, Azelaic Acid, Aloe barbadensis Leaf Juice, Sodium Ascorbyl Phosphate, Titanium Dioxide, Glycerin, Kojic Acid, Poloxamer 407, Glyceryl Stearate, Ethoxydiglycol, Hydroxypropyl Starch Phosphate, Alpha-Arbutin, Butylene Glycol Dicaprylate/Dicaprate, Cyclomethicone, Ethylhexyl Methoxycinnamate, Niacinamide, Di-C12-13 Alkyl Malate, Ceteareth-25, PEG-8 Beeswax, Stearic Acid, Tocopheryl Acetate, Retinyl Palmitate, Dimethicone, Alcohol, Behenyl Alcohol, Disodium Ethylene Dicocamide PEG-15 Disulfate, Citric Acid, Ascorbic Acid, Bisabolol, Salicylic Acid, Sclerotium Gum, Sorbitan Stearate, Stearyl Dimethicone, Sodium Lauroyl Lactylate, Aminoethylphosphinic Acid, Rumex occidentalis Extract, Acacia Senegal Gum, Glyceryl Stearate Citrate, Glycyrrhiza glabra Root Extract, Allantoin, Sodium Metabisulfite, Butylene Glycol, Phytic Acid, Xanthan Gum, Phenoxyethanol, Manganese Oxide, Tocopherol

Instructions for use

Do not use during pregnancy or breastfeeding. For external use only. Do not apply to damaged or irritated skin. Avoid contact with eyes and mucous membranes; rinse immediately with water if contact occurs. Wash hands after application. Do not use if known allergy to any ingredient. Keep out of reach of children.
Do not use simultaneously with glycolic acid products; keep at least one week apart. Avoid prolonged direct sun exposure. During the entire depigmentation process and afterwards, use sunscreen with at least SPF 50. Tingling, itching or mild burning in the first weeks are normal reactions. Maximum 0.5 ml per application; thicker layers may cause extreme dryness and flaking.

Product Safety & Contact

amaderm GmbH ,

Straßburger Str. 34
09120 Chemnitz
Deutschland
,

office@amaderm.de , +49 371 240 814 30