After the mask, the longer part of cosmelan begins: care at home. Here you can read how these weeks go, what feels normal and what to look out for with sun protection.
The key points in brief
- Home care with cosmelan 2 begins 48 to 72 hours after the mask and follows the plan of your skincare professional.
- cosmelan 2 Cream is intended for the time after cosmelan 1, not for use without the mask.
- Sun protection with at least SPF 50 belongs to it every day, during the brightening and afterwards too.
- Tingling, itching or a slight burning sensation in the first weeks are normal.
Two parts: the mask and the cream
cosmelan from mesoestetic has two parts. cosmelan 1 is a mask applied by a skincare professional, for example at a dermatologist or in a cosmetic facility. We do not sell this mask. Afterwards, you keep it on your skin at home for as long as your professional tells you: between 8 and 12 hours.
The second part is cosmelan 2, a cream for use at home. With it, you continue the care for an even-looking complexion that began with the mask. It is not intended for use without cosmelan 1.
The ingredient list of cosmelan 2 includes azelaic acid, kojic acid and phytic acid. These three acids can support a more even-looking complexion. In addition, there is vitamin C, on the ingredient list Ascorbic Acid and Sodium Ascorbyl Phosphate (more on this in our guide to vitamin C), as well as niacinamide and allantoin as soothing care. Retinyl palmitate is a vitamin A compound, but not retinol.
How home care works
You start 48 to 72 hours after you have removed the mask. Every time you apply cosmelan 2, the following applies:
- Cleanse your face.
- Apply a thin layer of cosmelan 2 to the areas named in your plan.
- Wash your hands afterwards.
- Keep the cream away from the eyes and mucous membranes. If it gets in, rinse immediately with water.
- During the day, you apply sun protection with at least SPF 50.
How often a day you apply cosmelan 2 changes over time. In the mesoestetic routine, the mask is followed by three phases at home, and in the last one the cream only goes on the skin in the evening. How many weeks each phase lasts and how much cream you use is set by your professional. Stick to this plan.
What is normal in the first weeks
Tingling, itching or a slight burning sensation are normal reactions to cosmelan 2 in the first weeks. Apply the cream thinly: thick layers can strongly dry out the skin and make it flake.
Do not apply cosmelan 2 to damaged or irritated skin. If your skin becomes very red, swells or becomes very dry, talk to your professional before you change anything about the amount. For this time, the Home Pack contains Melan Recovery, a soothing balm for sensitive, reddened skin. When you use it is also stated in your plan.
Do not use products with glycolic acid at the same time as cosmelan 2. For any other serum, peel or cream: ask your professional first. Combinations you put together yourself can disrupt the plan.
Sun protection: every day, and afterwards too
Throughout the entire brightening and afterwards, you need sun protection with at least SPF 50. Avoid long periods of direct sun during this time.
For the day, the Home Pack contains Mesoprotech Melan 130 Pigment Control, a sun protection with very high protection. In the morning, take at least half a teaspoon for the face and spread it over your face and neck, at least 30 minutes before you go out in the sun. If you are outside in the sun, after swimming or after sweating, reapply every 2 hours.
A review of studies on such spots names sun protection against UVA and UVB as an important step. It also notes that these spots often come back.
After cosmelan 2: care for the time afterwards
Even when the weeks with cosmelan 2 are over, daily sun protection with at least SPF 50 remains.
For skin prone to pigmentation spots, mesoestetic also offers Melan Tran3x Gel Cream, a light gel cream. It contains tranexamic acid, a substance that acts on the formation of melanin, the pigment of your skin. Niacinamide and kojic acid are added. Whether and from when it suits you after your cosmelan time is something to clarify with your professional.
In our shop
You can find the products for the time at home in our Pigmentation spots collection and under mesoestetic.
- cosmelan Home Pack: cosmelan 2, Melan Recovery and Mesoprotech Melan 130 Pigment Control in one set, for home care after cosmelan 1.
- cosmelan 2 Cream: the cream on its own, to restock during your plan.
- Mesoprotech Melan 130 Pigment Control: sun protection with very high protection, for every day during the brightening and afterwards.
- Melan Tran3x Gel Cream: light gel cream with tranexamic acid for skin prone to pigmentation spots.
Have you not had a cosmelan mask yet and are looking for care for dark spots? With our free AI skin analysis, you can find out which products suit your skin.
Frequently asked questions
What is a cosmelan treatment?
cosmelan is a method from mesoestetic for skin prone to pigmentation spots. It consists of the cosmelan 1 mask, applied by a skincare professional, and the cosmelan 2 cream for use at home. Daily sun protection with very high protection belongs to it.
Can I use cosmelan 2 without cosmelan 1?
No. cosmelan 2 Cream is intended for the time after the mask. If you are looking for care for pigmentation spots without a mask, take a look at our Pigmentation spots collection.
What to do if the skin is irritated with cosmelan 2?
A slight burning sensation, tingling and itching in the first weeks are normal. With strong redness, swelling or very dry skin, talk to your professional before you change the amount or frequency.
Can I use cosmelan during pregnancy?
The warning for cosmelan 2 Cream reads: "Do not use during pregnancy or breastfeeding." The same warning appears for the cosmelan Home Pack and Melan Tran3x Gel Cream.
Sources
- Gupta AK, Gover MD, Nouri K, Taylor S (2006): The treatment of melasma: a review of clinical trials. Journal of the American Academy of Dermatology 55(6):1048-1065. DOI 10.1016/j.jaad.2006.02.009, PMID 17097400.
- mesoestetic: cosmelan treatment, https://www.mesoestetic.com.au/professional/cosmelan-treatment.html, accessed on 07.11.2026.
- mesoestetic: cosmelan home pack, https://www.mesoestetic.com.au/cosmelan-home-pack.html, accessed on 07.11.2026.
- mesoestetic: cosmelan 2, https://mesoestetic.com.au/cosmelan-2.html, accessed on 07.11.2026.
